Search on: DNA POL II 
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Descriptor English:   DNA Polymerase II 
Descriptor Spanish:   ADN Polimerasa II 
Descriptor Portuguese:   DNA Polimerase II 
Synonyms English:   DNA Pol II
DNA Dependent DNA Polymerase II
DNA-Dependent DNA Polymerase II
DNA Polymerase epsilon  
Tree Number:   D08.811.913.696.445.308.300.230
Definition English:   A DNA-dependent DNA polymerase characterized in E. coli and other lower organisms. It may be present in higher organisms and has an intrinsic molecular activity only 5% of that of DNA Polymerase I. This polymerase has 3'-5' exonuclease activity, is effective only on duplex DNA with gaps or single-strand ends of less than 100 nucleotides as template, and is inhibited by sulfhydryl reagents. EC 2.7.7.7. 
History Note English:   84(77); for DNA POLYMERASE EPSILON use DNA POLYMERASE II (NM) 1994-97 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   4324 
Unique Identifier:   D004257 

Occurrence in VHL:
 

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